The problems related to cosmetics’ toxicity may be short term and go away if the use of the product is stopped. The chemical constituents present in cosmetics such as sunscreen, lipsticks, and hair dyes can cause adverse effects in the form of skin allergy, contact dermatitis, or other skin-related diseases. Thus, more focused and dedicated research is warranted to explore the effects of cosmetics on oxidative stress, glycoxidation of biomolecules, and photoproducts accumulation for its total human safety.Ĭosmetics (also referred to as personal care products) are products usually made to cleanse, enhance beauty, prevent skin tanning, increase attractiveness, enrich facial expressions, or altering the appearance without compromising the body’s functions or structure.
are performed under bright sunlight conditions. India has tropical weather conditions throughout the year and generally, a majority of human activities such as commerce, agriculture, sports, etc.
Sunlight-induced photodegradation and accumulation of cosmetic photoproducts are also a matter of serious concern. Natural antioxidants inhibit oxidative-stress-induced cosmetic toxicity. Oxidative stress induces membrane lipid peroxidation, glycoxidation, and protein covalent modifications, resulting in their dysfunction. Cosmetic phototoxicity may include percutaneous absorption, skin irritation, eye irritation, photosensitization, mutagenicity, and genotoxicity. Free-radicals-mediated DNA damage and oxidative stress are common consequences of cosmetic phototoxicity. The effect of light-induced photosensitization of cosmetic products, which results in the production of free radicals through type-I and type-II photosensitization mechanisms. Most cosmetic products have absorption maxima (λmax) in the range of visible light and UV-R. Sunlight has different wavelengths of light, which include UV-A, UV-B, UV-C, and other radiations.
Cosmetics are generally applied throughout the face and over the neck region. Cosmetic products include hair dyes, shampoos, skincare, sunscreens, kajal, and other makeup products. Cosmetics, commonly known as ‘makeup’ are products that can enhance the appearance of the human body.
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